Follow-up of children born with an umbilical arterial blood pH < 7

Article Abstract:

Infants born with an umbilical artery pH of less than 7 may do quite well if they survive the immediate postnatal period. A pH less than 7 indicates the infant is suffering from excessive acid in the blood and is thought to be a sign of future health problems. Researchers gave a developmental test to 25 children who had been born with an umbilical artery pH of less than 7. None of the children had an abnormal score. Three other children whose mothers refused a home visit to administer the test were found to have had normal development during previous visits. However, all 30 children originally identified at serious problems immediately after delivery. Seventy-seven percent had been admitted to the neonatal intensive care unit and 27% had been placed on a ventilator. Two infants died. An umbilical artery pH of less than 7 may not indicate serious developmental problems later in life but it may indicate those infants who may need intensive care following delivery.

Analysis, Measurement, Testing, Fetal blood, Child development, Hydrogen-ion concentration, pH measurement

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Newborn assessment and long-term adverse outcome: a systematic review

Article Abstract:

A low blood pH in the umbilical artery and the presence of severe encephalopathy are the best predictors of a long-term adverse outcome in newborn infants. Encephalopathy is a brain disorder that is usually caused by metabolic abnormalities. Researchers used meta-analysis to evaluate 42 studies that evaluated different predictors of a long-term adverse outcome. An umbilical artery pH less than 7 and a Sarnet grade III score were the best predictors of a long-term adverse outcome. A high Sarnet score indicates that the fetus has encephalopathy.

Prognosis, Fetal diseases

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Twin-to-twin transfusion syndrome at 11 weeks of gestation

Article Abstract:

The case of a monochorionic twin at 11+0 weeks of gestation with single increased nuchal translucency and normal karyotypes is presented. It is found that at 12+5 weeks of gestation, double intrauterine death was diagnosed, followed by delivery of a strikingly red and white fetus.

United States, Case studies, Fetofetal transfusion, Pregnancy, Complications of, Pregnancy complications

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